Male sexual health has often been surrounded by stigma, but the landscape is changing rapidly. Modern men are seeking long-term, natural, and effective solutions to challenges like erectile dysfunction (ED), Peyronie’s disease, or declining sexual performance with age. One of the most innovative therapies to emerge in the past decade is the P-Shot, also known as the Priapus Shot.
The P-Shot is not a drug or surgery. Instead, it’s a regenerative medicine procedure that uses your own blood — specifically, Platelet-Rich Plasma (PRP) — to stimulate healing, repair erectile tissue, and improve function.
As of 2025, the P-Shot is widely available across the world, used not only as a treatment for erectile dysfunction but also as a performance enhancer for men who want to optimize sexual health naturally.
This article provides the most detailed guide available — exploring the science, procedure, benefits, risks, results, and the role of the P-Shot in modern men’s health.
What is the P-Shot?
The Priapus Shot is a non-surgical injection treatment for male sexual performance and erectile dysfunction. P-shot is the perfect solution for treatment of erectile dysfunction.
The key component is Platelet-Rich Plasma (PRP), extracted from the patient’s blood. PRP contains growth factors and bioactive proteins that repair tissues, stimulate new blood vessel growth, and regenerate nerves.
When injected into the penis, PRP works by:
Improving blood flow into the erectile chambers
Enhancing sensitivity and nerve function
Stimulating repair of microvascular damage
Increasing tissue elasticity and strength
Unlike oral medications such as Viagra, which only increase blood flow temporarily, the P-Shot aims to restore natural erectile health.
The Evolution of the P-Shot
The concept of using PRP for regeneration is not new.
1980s: PRP was first used in dentistry and wound healing.
1990s–2000s: Orthopedics adopted PRP for tendon and joint injuries.
2010s: Aesthetic medicine introduced PRP facials and hair restoration.
2012: Dr. Charles Runels pioneered the P-Shot, applying PRP to male sexual health.
2020s: Clinics worldwide adopted advanced protocols, including PRFM (Platelet-Rich Fibrin Matrix) and combination therapies with shockwave treatment.
By 2025, the P-Shot is recognized as part of regenerative sexual medicine, alongside other therapies like stem cell injections and low-intensity extracorporeal shockwave therapy (Li-ESWT).
How Does the P-Shot Work?
The P-Shot works through the natural healing and regenerative capacity of PRP.
Growth Factors in PRP
PRP is rich in bioactive molecules such as:
VEGF (Vascular Endothelial Growth Factor): Stimulates new blood vessel growth.
PDGF (Platelet-Derived Growth Factor): Promotes tissue repair.
IGF (Insulin-like Growth Factor): Improves cell survival and regeneration.
NGF (Nerve Growth Factor): Encourages nerve repair and sensitivity.
Biological Impact on Erectile Tissue
When injected into penile tissue, these factors:
Trigger angiogenesis (new capillary growth).
Restore microvascular circulation for stronger erections.
Enhance nerve regeneration, boosting sensitivity.
Improve collagen and elastin production, making tissue more elastic.
Aid in breaking down scar tissue, helpful in Peyronie’s disease.
Step-by-Step P-Shot Procedure
Most P-Shot procedures take 45–60 minutes in a clinic setting.
Initial Consultation
Medical history and ED evaluation.
Discussion of expectations, risks, and alternatives.
Some doctors order penile Doppler ultrasound.
Blood Draw
About 20 ml of blood is taken from the patient’s arm.
PRP Preparation
Blood is spun in a centrifuge to separate platelets from red cells.
The resulting PRP is concentrated for injection.
Numbing
A topical anesthetic cream or penile nerve block ensures minimal discomfort.
Injection
Using fine needles, PRP is injected into the corpus cavernosum and sometimes the glans.
The process is guided for precision.
Aftercare
No downtime; patients resume normal activity immediately.
Some clinics recommend daily penile pump exercises for 4–6 weeks to maximize results.
Benefits of the P-Shot
Physical Benefits
Stronger, firmer erections
Increased penile sensitivity
Longer-lasting sexual performance
Reduction in Peyronie’s curvature and pain
Improved response to ED medications
Psychological Benefits
Restored confidence and self-esteem
Reduced anxiety about sexual performance
Better relationship satisfaction
Long-Term Advantages
Natural and drug-free
Low risk of side effects
Regenerates tissue instead of masking symptoms
Who is an Ideal Candidate?
The P-Shot can help men with:
Mild to moderate erectile dysfunction
Peyronie’s disease (scar tissue, curvature)
Loss of sensitivity during sex
Performance anxiety or stamina concerns
Men seeking natural enhancement without drugs
Who Should Avoid It?
Men with severe cardiovascular disease
Patients with active infections or blood disorders
Men with advanced nerve damage (e.g., after radical prostatectomy)
Risks and Side Effects
The P-Shot is generally safe since it uses autologous blood (your own).
Possible side effects include:
Mild bruising or swelling
Redness at injection site
Temporary soreness
Rare risk of infection
Most effects resolve within 24–72 hours.
Cost of P-Shot in 2025
The price varies depending on region, clinic reputation, and whether advanced PRFM is used.
Region | Price per Session |
|---|---|
USA | $1,500 – $2,500 |
UK | £1,000 – £1,800 |
Europe (avg) | €1,200 – €2,000 |
Canada | CAD $1,500 – $2,200 |
Middle East | $1,000 – $2,000 |
South Asia | $500 – $1,200 |
💡 Some men require 2–3 sessions for optimal results. Maintenance is usually every 12–18 months.
Results: What to Expect
Timeline
Week 1: Some men notice better sensitivity.
Weeks 3–6: Improved erections and stamina.
Months 2–3: Maximum benefits — firmer erections, improved curvature (if Peyronie’s).
Months 6–12: Sustained results with proper lifestyle.
Duration
Results typically last 12–18 months.
Booster sessions can extend benefits.
Research and Evidence
Clinical Findings
Studies between 2017–2024 found that PRP therapy improves erectile function scores in men with mild to moderate ED.
Research on Peyronie’s disease shows reduced curvature and pain after PRP injections.
Patients often report better satisfaction and confidence, even when objective measures show moderate improvement.
Limitations
Not yet FDA-approved specifically for ED.
Large-scale randomized clinical trials are still limited.
Still, the P-Shot is considered safe, minimally invasive, and promising.
P-Shot vs Other Treatments
Treatment | Mechanism | Duration | Invasiveness | Notes |
|---|---|---|---|---|
Viagra/Cialis | Increases blood flow | Hours | None | Quick fix, side effects |
Shockwave Therapy | Stimulates vessels | 6–12 mo | None | Often combined with P-Shot |
Penile Implants | Mechanical prosthesis | Permanent | Surgical | For severe ED only |
P-Shot | Regenerates tissue | 12–18 mo | Minimally invasive | Natural, long-term |
Global Trends in 2025
North America & Europe: P-Shot is mainstream, often combined with shockwave therapy.
Asia: Growing demand in India, Pakistan, Thailand, and South Korea, where medical tourism is strong.
Middle East: Popular among men seeking discreet, non-drug solutions.
Australia: Offered by sexual wellness and urology clinics.
Lifestyle Habits That Enhance Results
The P-Shot works best when combined with healthy habits:
Regular exercise (boosts testosterone and circulation).
Heart-healthy diet (Mediterranean-style diet).
Quit smoking (smoking severely damages penile blood vessels).
Manage stress (chronic stress raises cortisol, lowering performance).
Sleep 7–9 hours (improves natural testosterone production).
Common Myths
Myth: The P-Shot enlarges the penis permanently.
Fact: It may improve girth slightly due to better circulation, but it is not a size-enhancement surgery.Myth: Results are instant and permanent.
Fact: Benefits build gradually over weeks and last 12–18 months.Myth: Only older men need it.
Fact: Many younger men use it for stamina and sensitivity.
FAQs
Q1: Is the P-Shot painful?
No, numbing cream or local anesthesia makes it tolerable. Most patients report mild discomfort.
Q2: Can I combine it with Viagra?
Yes, many men find improved responsiveness to oral ED drugs after the P-Shot.
Q3: How soon can I have sex after the P-Shot?
Usually within 24–48 hours.
Q4: Will it help after prostate surgery?
Results vary. Some men regain partial sensitivity, but severe nerve damage may not fully respond.
Q5: Are there alternatives?
Yes — shockwave therapy, stem cell injections, or penile implants, depending on severity.
Conclusion
The P-Shot treatment has become one of the most promising breakthroughs in men’s sexual health. By using platelet-rich plasma, it naturally restores erectile function, improves sensitivity, and enhances overall sexual performance.
Unlike pills or surgery, the P-Shot offers a regenerative approach — tackling the root causes of erectile dysfunction rather than just masking symptoms.
While not a miracle cure, it’s a safe, effective, and minimally invasive solution for men struggling with ED, Peyronie’s disease, or reduced performance. In 2025, the P-Shot is no longer an experimental therapy — it’s a mainstream option for men worldwide who want to reclaim their sexual vitality.
